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primary human cardiofibroblasts  (PromoCell)


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    PromoCell primary human cardiofibroblasts
    Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human <t>cardiofibroblasts.</t>
    Primary Human Cardiofibroblasts, supplied by PromoCell, used in various techniques. Bioz Stars score: 96/100, based on 258 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary human cardiofibroblasts/product/PromoCell
    Average 96 stars, based on 258 article reviews
    primary human cardiofibroblasts - by Bioz Stars, 2026-06
    96/100 stars

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    1) Product Images from "Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression"

    Article Title: Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

    Journal: Cells

    doi: 10.3390/cells10040818

    Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts.
    Figure Legend Snippet: Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts.

    Techniques Used:

    Selected hints of the significantly dysregulated canonical pathways in hCM ( A ) and hCF ( B ) treated with sera from acute MCD patients vs. healthy controls. Selected hints of the significantly dysregulated cardiotoxicity functions in hCM ( C ) and hCF ( D ) treated with sera from acute MCD patients vs. healthy controls. Identified with Ingenuity Pathway Analysis (IPA) using respectively 1138 and 1050 protein-coding transcripts that changed significantly. Fisher’s exact test, p < 0.05. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts; ERK5, extracellular-signal-regulated kinase 5; iNOS, inducible nitric oxide synthase; PAK, p21-activated kinases; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-7, interleukin 7; STAT3, signal transducer and activator of transcription 3; IL-6, interleukin 6.
    Figure Legend Snippet: Selected hints of the significantly dysregulated canonical pathways in hCM ( A ) and hCF ( B ) treated with sera from acute MCD patients vs. healthy controls. Selected hints of the significantly dysregulated cardiotoxicity functions in hCM ( C ) and hCF ( D ) treated with sera from acute MCD patients vs. healthy controls. Identified with Ingenuity Pathway Analysis (IPA) using respectively 1138 and 1050 protein-coding transcripts that changed significantly. Fisher’s exact test, p < 0.05. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts; ERK5, extracellular-signal-regulated kinase 5; iNOS, inducible nitric oxide synthase; PAK, p21-activated kinases; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-7, interleukin 7; STAT3, signal transducer and activator of transcription 3; IL-6, interleukin 6.

    Techniques Used:

    The expression of TFR1 in human cardiomyocytes ( A – C ) and in human cardiofibroblasts ( D – F ) treated with patients’ sera at the mRNA and protein level, together with representative immunoblots ( C , F ). ANNOVA test followed by Dunnett’s multiple comparisons test or Kruskal–Wallis test followed by Dunn’s multiple comparisons test (depending on data normality). * p < 0.05; ** p < 0.01; *** p < 0.001. The association between the protein level of TFR1 in human cardiac myocytes treated with patient sera and markers of iron status in patients’ peripheral blood i.e., transferrin saturation ( G ), serum iron ( H ), and serum ferritin ( I ). Gene and protein expressions were normalized to mean value in control group. Spearman’s rank correlation. * p < 0.05; ** p < 0.01; *** p < 0.001. Abbreviations: AU, arbitrary units; C, healthy controls, H, hospitalization (acute phase); 6wk, after 6 weeks of clinical recovery; TFR1, transferrin receptor 1; TSAT, transferrin saturation.
    Figure Legend Snippet: The expression of TFR1 in human cardiomyocytes ( A – C ) and in human cardiofibroblasts ( D – F ) treated with patients’ sera at the mRNA and protein level, together with representative immunoblots ( C , F ). ANNOVA test followed by Dunnett’s multiple comparisons test or Kruskal–Wallis test followed by Dunn’s multiple comparisons test (depending on data normality). * p < 0.05; ** p < 0.01; *** p < 0.001. The association between the protein level of TFR1 in human cardiac myocytes treated with patient sera and markers of iron status in patients’ peripheral blood i.e., transferrin saturation ( G ), serum iron ( H ), and serum ferritin ( I ). Gene and protein expressions were normalized to mean value in control group. Spearman’s rank correlation. * p < 0.05; ** p < 0.01; *** p < 0.001. Abbreviations: AU, arbitrary units; C, healthy controls, H, hospitalization (acute phase); 6wk, after 6 weeks of clinical recovery; TFR1, transferrin receptor 1; TSAT, transferrin saturation.

    Techniques Used: Expressing, Western Blot



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    primary human cardiofibroblasts  (PromoCell)
    96
    PromoCell primary human cardiofibroblasts
    Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human <t>cardiofibroblasts.</t>
    Primary Human Cardiofibroblasts, supplied by PromoCell, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary human cardiofibroblasts/product/PromoCell
    Average 96 stars, based on 1 article reviews
    primary human cardiofibroblasts - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts.

    Journal: Cells

    Article Title: Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

    doi: 10.3390/cells10040818

    Figure Lengend Snippet: Venn diagram ( A ) of overlapped up- and downregulated genes detected between two cell types (hCF and hCM). Significantly changed genes in hCM ( B ) and hCF ( C ) treated with sera from acute MCD patients vs. healthy controls. Student’ t -test, p FDR < 0.1, n = 3 per group. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts.

    Article Snippet: Primary human cardiofibroblasts (hCF, PromoCell) were precultured in Fibroblast Growth Medium supplemented with the recommended Supplemented Mix (PromoCell) and passaged 5 times before the experiment.

    Techniques:

    Selected hints of the significantly dysregulated canonical pathways in hCM ( A ) and hCF ( B ) treated with sera from acute MCD patients vs. healthy controls. Selected hints of the significantly dysregulated cardiotoxicity functions in hCM ( C ) and hCF ( D ) treated with sera from acute MCD patients vs. healthy controls. Identified with Ingenuity Pathway Analysis (IPA) using respectively 1138 and 1050 protein-coding transcripts that changed significantly. Fisher’s exact test, p < 0.05. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts; ERK5, extracellular-signal-regulated kinase 5; iNOS, inducible nitric oxide synthase; PAK, p21-activated kinases; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-7, interleukin 7; STAT3, signal transducer and activator of transcription 3; IL-6, interleukin 6.

    Journal: Cells

    Article Title: Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

    doi: 10.3390/cells10040818

    Figure Lengend Snippet: Selected hints of the significantly dysregulated canonical pathways in hCM ( A ) and hCF ( B ) treated with sera from acute MCD patients vs. healthy controls. Selected hints of the significantly dysregulated cardiotoxicity functions in hCM ( C ) and hCF ( D ) treated with sera from acute MCD patients vs. healthy controls. Identified with Ingenuity Pathway Analysis (IPA) using respectively 1138 and 1050 protein-coding transcripts that changed significantly. Fisher’s exact test, p < 0.05. Abbreviations: hCM, human cardiomyocytes; hCF, human cardiofibroblasts; ERK5, extracellular-signal-regulated kinase 5; iNOS, inducible nitric oxide synthase; PAK, p21-activated kinases; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-7, interleukin 7; STAT3, signal transducer and activator of transcription 3; IL-6, interleukin 6.

    Article Snippet: Primary human cardiofibroblasts (hCF, PromoCell) were precultured in Fibroblast Growth Medium supplemented with the recommended Supplemented Mix (PromoCell) and passaged 5 times before the experiment.

    Techniques:

    The expression of TFR1 in human cardiomyocytes ( A – C ) and in human cardiofibroblasts ( D – F ) treated with patients’ sera at the mRNA and protein level, together with representative immunoblots ( C , F ). ANNOVA test followed by Dunnett’s multiple comparisons test or Kruskal–Wallis test followed by Dunn’s multiple comparisons test (depending on data normality). * p < 0.05; ** p < 0.01; *** p < 0.001. The association between the protein level of TFR1 in human cardiac myocytes treated with patient sera and markers of iron status in patients’ peripheral blood i.e., transferrin saturation ( G ), serum iron ( H ), and serum ferritin ( I ). Gene and protein expressions were normalized to mean value in control group. Spearman’s rank correlation. * p < 0.05; ** p < 0.01; *** p < 0.001. Abbreviations: AU, arbitrary units; C, healthy controls, H, hospitalization (acute phase); 6wk, after 6 weeks of clinical recovery; TFR1, transferrin receptor 1; TSAT, transferrin saturation.

    Journal: Cells

    Article Title: Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

    doi: 10.3390/cells10040818

    Figure Lengend Snippet: The expression of TFR1 in human cardiomyocytes ( A – C ) and in human cardiofibroblasts ( D – F ) treated with patients’ sera at the mRNA and protein level, together with representative immunoblots ( C , F ). ANNOVA test followed by Dunnett’s multiple comparisons test or Kruskal–Wallis test followed by Dunn’s multiple comparisons test (depending on data normality). * p < 0.05; ** p < 0.01; *** p < 0.001. The association between the protein level of TFR1 in human cardiac myocytes treated with patient sera and markers of iron status in patients’ peripheral blood i.e., transferrin saturation ( G ), serum iron ( H ), and serum ferritin ( I ). Gene and protein expressions were normalized to mean value in control group. Spearman’s rank correlation. * p < 0.05; ** p < 0.01; *** p < 0.001. Abbreviations: AU, arbitrary units; C, healthy controls, H, hospitalization (acute phase); 6wk, after 6 weeks of clinical recovery; TFR1, transferrin receptor 1; TSAT, transferrin saturation.

    Article Snippet: Primary human cardiofibroblasts (hCF, PromoCell) were precultured in Fibroblast Growth Medium supplemented with the recommended Supplemented Mix (PromoCell) and passaged 5 times before the experiment.

    Techniques: Expressing, Western Blot